btaf430
1 btaf430
library(survival)
library(mgcv)
library(spatstat.geom)
library(groupedHyperframe)
library(hyper.gam)
library(spatstat.mc)
library(Qindex.data)unique_or_identity = \(x) {
u <- unique(x)
if (length(u) == 1L) return(u)
return(x)
}Code
Ki67 = Qindex.data::Ki67 |>
dplyr::rename(
patientID = PATIENT_ID,
age = AGE_AT_DX,
x = inner_x,
y = inner_y,
node = NodeSt,
HR = HRpos,
Her2 = Her2_path_qIF,
histology = HistologicalGrade,
adj_chemo = RadjCHEMO,
adj_rad = RadjRAD,
horm = HORM_4cat
) |>
within(expr = {
logKi67 = log1p(Marker); Marker = NULL
race = factor(RACE); RACE = NULL
node[node == -1L] = NA_integer_; node = as.logical(node);
HR = as.logical(HR)
Her2 = as.logical(Her2)
adj_chemo[adj_chemo == 0] = NA_integer_; adj_chemo = (adj_chemo == 1L)
adj_rad[adj_rad == 0] = NA_integer_; adj_rad = (adj_rad == 1L)
horm[horm == 0L] = NA_integer_; horm = structure(horm, levels = c('not indicated', 'done', 'recommended, but not done'), class = 'factor');
MSI = NULL
PFS = survival::Surv(time = RECFREESURV_MO, event = RECURRENCE); RECURRENCE = NULL; RECFREESURV_MO = NULL
})The object Ki67q is a hyper data frame with
Ki67q
Ki67qHyperframe:
patientID tissueID age node Tstage HR histology Her2 adj_chemo adj_rad
1 PT00037 (factor) 66 TRUE 2 TRUE 3 TRUE FALSE FALSE
2 PT00039 (factor) 42 FALSE 1 TRUE 3 FALSE FALSE FALSE
3 PT00040 (factor) 60 FALSE 1 TRUE 3 FALSE NA FALSE
4 PT00042 (factor) 53 TRUE 1 TRUE 3 FALSE TRUE FALSE
5 PT00054 (factor) 52 TRUE 1 TRUE 3 FALSE TRUE TRUE
6 PT00059 (factor) 51 TRUE 4 TRUE 2 TRUE FALSE TRUE
7 PT00062 (factor) 50 TRUE 2 TRUE 3 FALSE FALSE FALSE
8 PT00068 (factor) 37 TRUE 2 TRUE 2 TRUE FALSE FALSE
9 PT00082 (factor) 68 FALSE 2 TRUE 3 TRUE FALSE FALSE
10 PT00084 (factor) 55 FALSE 2 TRUE 2 TRUE TRUE FALSE
11 PT00085 (factor) 72 FALSE 1 TRUE 2 FALSE FALSE FALSE
12 PT00086 (factor) 43 TRUE 2 TRUE 3 FALSE FALSE FALSE
13 PT00087 (factor) 36 TRUE 3 TRUE 3 FALSE TRUE TRUE
14 PT00088 (factor) 37 TRUE 2 TRUE 1 FALSE TRUE FALSE
15 PT00089 (factor) 69 FALSE 1 TRUE 1 FALSE FALSE FALSE
16 PT00090 (factor) 63 TRUE 2 TRUE 2 FALSE FALSE FALSE
17 PT00093 (factor) 58 FALSE 1 TRUE 3 FALSE FALSE FALSE
18 PT00097 (factor) 60 TRUE 2 TRUE 2 TRUE FALSE FALSE
19 PT00100 (factor) 50 FALSE 1 TRUE 2 FALSE FALSE FALSE
20 PT00186 (factor) 70 TRUE 2 TRUE 1 FALSE FALSE TRUE
21 PT00188 (factor) 43 FALSE 2 TRUE 2 FALSE TRUE TRUE
22 PT00194 (factor) 48 TRUE 2 TRUE 1 FALSE TRUE FALSE
23 PT00202 (factor) 68 TRUE 1 TRUE 2 FALSE FALSE FALSE
24 PT00210 (factor) 73 TRUE 4 TRUE 2 FALSE FALSE TRUE
25 PT00211 (factor) 51 FALSE 2 TRUE 1 FALSE FALSE FALSE
26 PT00212 (factor) 51 FALSE 2 TRUE 2 FALSE FALSE TRUE
27 PT00213 (factor) 73 FALSE 2 TRUE 1 FALSE FALSE FALSE
28 PT00214 (factor) 80 FALSE 1 TRUE 1 FALSE FALSE FALSE
29 PT00215 (factor) 56 FALSE 1 TRUE 1 FALSE TRUE FALSE
30 PT00216 (factor) 77 TRUE 2 TRUE 2 FALSE FALSE FALSE
31 PT00218 (factor) 36 FALSE 1 TRUE 2 FALSE FALSE FALSE
32 PT00220 (factor) 48 TRUE 2 TRUE 2 FALSE TRUE TRUE
33 PT00221 (factor) 73 FALSE 1 TRUE 1 FALSE FALSE TRUE
34 PT00222 (factor) 56 TRUE 1 TRUE 1 FALSE TRUE FALSE
35 PT00226 (factor) 60 FALSE 1 TRUE 2 FALSE FALSE TRUE
36 PT00228 (factor) 76 FALSE 4 TRUE 2 FALSE FALSE FALSE
37 PT00230 (factor) 72 FALSE 1 TRUE 2 FALSE FALSE TRUE
38 PT00232 (factor) 63 FALSE 1 TRUE 2 FALSE FALSE TRUE
39 PT00234 (factor) 48 TRUE 1 TRUE 3 FALSE TRUE TRUE
40 PT00240 (factor) 59 FALSE 2 TRUE 1 FALSE FALSE FALSE
41 PT00241 (factor) 58 FALSE 2 TRUE 2 FALSE FALSE FALSE
42 PT00242 (factor) 71 FALSE 2 TRUE 3 FALSE FALSE FALSE
43 PT00243 (factor) 68 FALSE 1 TRUE 1 FALSE FALSE FALSE
44 PT00244 (factor) 36 TRUE 2 TRUE 3 FALSE FALSE FALSE
45 PT00251 (factor) 42 FALSE 1 TRUE 1 FALSE FALSE FALSE
46 PT00258 (factor) 80 FALSE 2 TRUE 1 FALSE FALSE FALSE
47 PT00260 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE TRUE
48 PT00262 (factor) 67 TRUE 2 TRUE 1 FALSE TRUE TRUE
49 PT00263 (factor) 53 TRUE 2 TRUE 2 FALSE TRUE FALSE
50 PT00270 (factor) 78 FALSE 1 TRUE 2 FALSE FALSE TRUE
51 PT00275 (factor) 46 TRUE 1 TRUE 1 FALSE TRUE TRUE
52 PT00281 (factor) 85 TRUE 1 TRUE 2 FALSE FALSE FALSE
53 PT00283 (factor) 48 TRUE 2 TRUE 2 FALSE TRUE FALSE
54 PT00293 (factor) 55 FALSE 1 TRUE 2 FALSE FALSE TRUE
55 PT00298 (factor) 45 TRUE 1 TRUE 2 FALSE TRUE FALSE
56 PT00302 (factor) 47 TRUE 2 TRUE 1 FALSE TRUE FALSE
57 PT00303 (factor) 80 FALSE 1 TRUE 2 FALSE FALSE FALSE
58 PT00304 (factor) 49 FALSE 1 TRUE 1 FALSE TRUE FALSE
59 PT00308 (factor) 55 TRUE 1 TRUE 2 FALSE TRUE TRUE
60 PT00315 (factor) 48 TRUE 2 TRUE 1 NA TRUE FALSE
61 PT00317 (factor) 46 FALSE 2 TRUE 1 FALSE FALSE FALSE
62 PT00319 (factor) 45 TRUE 1 TRUE 2 FALSE TRUE FALSE
63 PT00322 (factor) 63 FALSE 1 TRUE 2 FALSE FALSE FALSE
64 PT00323 (factor) 82 FALSE 2 TRUE 3 FALSE FALSE FALSE
65 PT00324 (factor) 64 TRUE 1 TRUE 2 FALSE TRUE FALSE
66 PT00332 (factor) 51 FALSE 1 TRUE 2 TRUE FALSE TRUE
67 PT00333 (factor) 63 FALSE 2 TRUE 1 FALSE TRUE FALSE
68 PT00335 (factor) 44 FALSE 2 TRUE 3 FALSE TRUE FALSE
69 PT00338 (factor) 39 FALSE 1 TRUE 2 FALSE FALSE FALSE
70 PT00344 (factor) 35 TRUE 3 TRUE 2 FALSE TRUE TRUE
71 PT00348 (factor) 63 FALSE 1 TRUE 2 NA FALSE TRUE
72 PT00349 (factor) 42 FALSE 2 TRUE 2 FALSE TRUE TRUE
73 PT00351 (factor) 67 FALSE 1 TRUE 2 FALSE FALSE TRUE
74 PT00352 (factor) 66 FALSE 1 TRUE 2 FALSE FALSE TRUE
75 PT00355 (factor) 78 TRUE 1 TRUE 2 FALSE FALSE FALSE
76 PT00357 (factor) 50 TRUE 1 TRUE 1 FALSE FALSE FALSE
77 PT00368 (factor) 64 FALSE 1 TRUE 3 TRUE FALSE FALSE
78 PT00380 (factor) 70 FALSE 1 TRUE 3 FALSE FALSE TRUE
79 PT00384 (factor) 65 TRUE 2 TRUE 2 FALSE FALSE FALSE
80 PT00385 (factor) 51 TRUE 2 TRUE 2 FALSE TRUE FALSE
81 PT00386 (factor) 69 FALSE 2 TRUE 2 FALSE FALSE TRUE
82 PT00388 (factor) 73 FALSE 1 TRUE 1 FALSE FALSE TRUE
83 PT00393 (factor) 58 FALSE 2 TRUE 2 FALSE FALSE TRUE
84 PT00395 (factor) 62 FALSE 3 TRUE 3 FALSE TRUE FALSE
85 PT00396 (factor) 67 TRUE 2 TRUE 1 FALSE FALSE TRUE
86 PT00397 (factor) 32 FALSE 3 TRUE 2 FALSE FALSE FALSE
87 PT00401 (factor) 61 TRUE 2 TRUE 2 FALSE NA NA
88 PT00413 (factor) 71 FALSE 2 TRUE 3 FALSE FALSE FALSE
89 PT00422 (factor) 68 FALSE 1 TRUE 2 FALSE FALSE FALSE
90 PT00423 (factor) 70 FALSE 4 TRUE 2 NA TRUE TRUE
91 PT00424 (factor) 37 FALSE 1 TRUE 3 FALSE TRUE FALSE
92 PT00425 (factor) 79 FALSE 1 TRUE 1 FALSE FALSE FALSE
93 PT00426 (factor) 65 FALSE 1 TRUE 1 FALSE FALSE FALSE
94 PT00427 (factor) 65 FALSE 1 TRUE 2 TRUE FALSE FALSE
95 PT00428 (factor) 45 FALSE 1 TRUE 2 FALSE TRUE TRUE
96 PT00433 (factor) 65 TRUE 2 TRUE 1 FALSE FALSE FALSE
97 PT00434 (factor) 66 TRUE 1 TRUE 1 FALSE FALSE FALSE
98 PT00438 (factor) 55 TRUE 1 TRUE 2 FALSE TRUE TRUE
99 PT00439 (factor) 70 TRUE 2 TRUE 1 FALSE FALSE FALSE
100 PT00441 (factor) 67 FALSE 1 TRUE 3 TRUE TRUE FALSE
101 PT00442 (factor) 50 FALSE 2 TRUE 1 FALSE FALSE TRUE
102 PT00443 (factor) 73 FALSE 2 TRUE 2 FALSE FALSE FALSE
103 PT00448 (factor) 69 TRUE 1 TRUE 3 FALSE FALSE FALSE
104 PT00449 (factor) 70 FALSE 1 TRUE 2 FALSE FALSE TRUE
105 PT00450 (factor) 62 FALSE 1 TRUE 2 FALSE FALSE TRUE
106 PT00451 (factor) 62 FALSE 2 TRUE 2 FALSE FALSE FALSE
107 PT00455 (factor) 58 TRUE 1 TRUE 3 FALSE FALSE TRUE
108 PT00456 (factor) 71 FALSE 1 TRUE 1 FALSE FALSE TRUE
109 PT00462 (factor) 71 FALSE 2 TRUE 2 FALSE FALSE FALSE
110 PT00468 (factor) 61 FALSE 2 TRUE 3 FALSE FALSE FALSE
111 PT00469 (factor) 69 FALSE 1 TRUE 2 FALSE FALSE FALSE
112 PT00472 (factor) 55 NA 1 TRUE 1 FALSE FALSE FALSE
113 PT00478 (factor) 66 FALSE 2 TRUE 2 FALSE FALSE FALSE
114 PT00486 (factor) 59 TRUE 1 TRUE 2 FALSE FALSE TRUE
115 PT00488 (factor) 40 TRUE 1 TRUE 1 NA TRUE TRUE
116 PT00493 (factor) 37 FALSE 1 TRUE 1 FALSE FALSE FALSE
117 PT00497 (factor) 59 FALSE 2 TRUE 2 FALSE FALSE TRUE
118 PT00500 (factor) 43 TRUE 2 TRUE 2 FALSE TRUE TRUE
119 PT00502 (factor) 78 FALSE 1 TRUE 2 FALSE FALSE TRUE
120 PT00504 (factor) 78 TRUE 1 TRUE 3 FALSE TRUE TRUE
121 PT00505 (factor) 70 FALSE 2 TRUE 3 TRUE FALSE FALSE
122 PT00506 (factor) 67 FALSE 2 TRUE 3 TRUE FALSE FALSE
123 PT00507 (factor) 70 TRUE 2 TRUE 2 FALSE FALSE TRUE
124 PT00511 (factor) 71 TRUE 2 TRUE 2 FALSE TRUE TRUE
125 PT00512 (factor) 56 FALSE 2 TRUE 2 FALSE TRUE TRUE
126 PT00514 (factor) 72 FALSE 1 TRUE 3 FALSE FALSE TRUE
127 PT00515 (factor) 81 FALSE 1 TRUE 2 FALSE FALSE TRUE
128 PT00516 (factor) 62 FALSE 2 TRUE 2 FALSE FALSE FALSE
129 PT00517 (factor) 85 FALSE 1 TRUE 2 FALSE FALSE FALSE
130 PT00518 (factor) 62 FALSE 1 TRUE 1 FALSE FALSE TRUE
131 PT00519 (factor) 42 FALSE 1 TRUE 1 FALSE TRUE TRUE
132 PT00522 (factor) 60 FALSE 1 TRUE 1 FALSE TRUE FALSE
133 PT00525 (factor) 74 FALSE 2 TRUE 1 FALSE FALSE TRUE
134 PT00526 (factor) 55 FALSE 2 TRUE 3 FALSE FALSE FALSE
135 PT00527 (factor) 56 TRUE 2 TRUE 1 FALSE FALSE FALSE
136 PT00529 (factor) 56 TRUE 1 TRUE 1 FALSE TRUE FALSE
137 PT00530 (factor) 66 FALSE 1 TRUE 1 FALSE FALSE TRUE
138 PT00541 (factor) 45 TRUE 1 TRUE 1 NA TRUE FALSE
139 PT00546 (factor) 34 TRUE 1 TRUE 2 FALSE TRUE TRUE
140 PT00547 (factor) 59 FALSE 1 TRUE 2 FALSE FALSE FALSE
141 PT00550 (factor) 56 FALSE 2 TRUE 3 TRUE FALSE TRUE
142 PT00551 (factor) 44 TRUE 2 TRUE 2 FALSE TRUE TRUE
143 PT00554 (factor) 53 FALSE 1 TRUE 2 FALSE TRUE FALSE
144 PT00555 (factor) 62 FALSE 1 TRUE 2 FALSE FALSE TRUE
145 PT00557 (factor) 45 FALSE 1 TRUE 3 FALSE FALSE FALSE
146 PT00561 (factor) 35 FALSE 1 TRUE 1 NA FALSE FALSE
147 PT00562 (factor) 63 TRUE 1 TRUE 1 FALSE TRUE FALSE
148 PT00566 (factor) 68 FALSE 1 TRUE 2 FALSE FALSE TRUE
149 PT00567 (factor) 41 FALSE 2 TRUE 2 FALSE FALSE FALSE
150 PT00576 (factor) 40 TRUE 2 TRUE 2 FALSE TRUE TRUE
151 PT00577 (factor) 79 FALSE 1 TRUE 3 FALSE FALSE TRUE
152 PT00585 (factor) 50 TRUE 1 TRUE 3 TRUE TRUE TRUE
153 PT00586 (factor) 72 FALSE 1 TRUE 1 FALSE FALSE FALSE
154 PT00588 (factor) 70 FALSE 1 TRUE 1 FALSE FALSE FALSE
155 PT00589 (factor) 69 TRUE 2 TRUE 1 FALSE FALSE TRUE
156 PT00594 (factor) 69 FALSE 1 TRUE 1 FALSE FALSE TRUE
157 PT00595 (factor) 64 TRUE 1 TRUE 2 FALSE TRUE FALSE
158 PT00596 (factor) 75 FALSE 1 TRUE 1 FALSE FALSE TRUE
159 PT00597 (factor) 46 FALSE 2 TRUE 1 FALSE TRUE FALSE
160 PT00600 (factor) 60 FALSE 1 TRUE 2 FALSE FALSE TRUE
161 PT00601 (factor) 58 TRUE 3 TRUE 2 FALSE TRUE FALSE
162 PT00603 (factor) 47 TRUE 2 TRUE 2 FALSE TRUE TRUE
163 PT00606 (factor) 47 FALSE 1 TRUE 1 FALSE FALSE FALSE
164 PT00608 (factor) 47 FALSE 1 TRUE 2 FALSE FALSE FALSE
165 PT00610 (factor) 56 FALSE 1 TRUE 3 FALSE FALSE TRUE
166 PT00613 (factor) 45 FALSE 1 TRUE 2 FALSE FALSE TRUE
167 PT00614 (factor) 47 FALSE 1 TRUE 1 FALSE FALSE TRUE
168 PT00616 (factor) 48 TRUE 2 TRUE 1 FALSE TRUE FALSE
169 PT00621 (factor) 79 FALSE 1 TRUE 2 FALSE FALSE TRUE
170 PT00626 (factor) 76 FALSE 1 TRUE 1 FALSE FALSE FALSE
171 PT00627 (factor) 54 TRUE 1 TRUE 1 FALSE TRUE TRUE
172 PT00629 (factor) 52 TRUE 1 TRUE 1 FALSE FALSE FALSE
173 PT00633 (factor) 42 TRUE 1 TRUE 3 FALSE TRUE TRUE
174 PT00637 (factor) 55 FALSE 1 TRUE 2 TRUE FALSE FALSE
175 PT00638 (factor) 49 FALSE 1 TRUE 1 FALSE FALSE TRUE
176 PT00639 (factor) 51 TRUE 3 TRUE 1 FALSE TRUE TRUE
177 PT00642 (factor) 75 FALSE 1 TRUE 1 FALSE FALSE TRUE
178 PT00644 (factor) 49 FALSE 1 TRUE 1 FALSE FALSE TRUE
179 PT00646 (factor) 53 TRUE 3 TRUE 3 FALSE TRUE TRUE
180 PT00648 (factor) 46 FALSE 1 TRUE 1 FALSE FALSE TRUE
181 PT00653 (factor) 67 FALSE 4 TRUE 3 FALSE FALSE FALSE
182 PT00654 (factor) 55 TRUE 1 TRUE 1 FALSE TRUE TRUE
183 PT00657 (factor) 62 TRUE 2 TRUE 3 FALSE TRUE FALSE
184 PT00658 (factor) 64 FALSE 1 TRUE 1 TRUE FALSE FALSE
185 PT00659 (factor) 75 FALSE 1 TRUE 2 FALSE FALSE TRUE
186 PT00661 (factor) 54 FALSE 1 TRUE 3 TRUE TRUE TRUE
187 PT00665 (factor) 58 TRUE 4 TRUE 2 FALSE TRUE TRUE
188 PT00666 (factor) 78 FALSE 1 TRUE 1 FALSE FALSE TRUE
189 PT00669 (factor) 42 TRUE 2 TRUE 3 FALSE FALSE TRUE
190 PT00673 (factor) 56 FALSE 1 TRUE 3 FALSE FALSE FALSE
191 PT00675 (factor) 51 FALSE 1 TRUE 1 FALSE FALSE TRUE
192 PT00683 (factor) 65 TRUE 2 TRUE 2 FALSE TRUE TRUE
193 PT00684 (factor) 52 FALSE 1 TRUE 1 FALSE FALSE TRUE
194 PT00690 (factor) 68 FALSE 1 TRUE 2 FALSE FALSE FALSE
195 PT00694 (factor) 57 FALSE 1 TRUE 1 TRUE FALSE TRUE
196 PT00700 (factor) 39 FALSE 2 TRUE 3 FALSE FALSE FALSE
197 PT00703 (factor) 50 FALSE 1 TRUE 2 FALSE FALSE TRUE
198 PT00704 (factor) 50 TRUE 1 TRUE 2 FALSE TRUE FALSE
199 PT00705 (factor) 65 FALSE 1 TRUE 1 FALSE FALSE FALSE
200 PT00706 (factor) 45 FALSE 1 TRUE 3 FALSE FALSE FALSE
201 PT00707 (factor) 62 TRUE 1 TRUE 2 FALSE FALSE FALSE
202 PT00708 (factor) 82 FALSE 1 TRUE 3 FALSE FALSE FALSE
203 PT00710 (factor) 64 FALSE 1 TRUE 1 FALSE FALSE FALSE
204 PT00711 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE FALSE
205 PT00712 (factor) 65 FALSE 1 TRUE 1 FALSE FALSE TRUE
206 PT00714 (factor) 49 FALSE 1 TRUE 3 TRUE FALSE FALSE
207 PT00716 (factor) 50 TRUE 3 TRUE 1 FALSE TRUE FALSE
208 PT00718 (factor) 57 FALSE 1 TRUE 2 FALSE FALSE TRUE
209 PT00719 (factor) 77 FALSE 1 TRUE 1 FALSE FALSE FALSE
210 PT00721 (factor) 41 FALSE 1 TRUE 2 FALSE FALSE FALSE
211 PT00724 (factor) 51 FALSE 2 TRUE 2 FALSE TRUE TRUE
212 PT00730 (factor) 52 FALSE 1 TRUE 2 FALSE FALSE FALSE
213 PT00732 (factor) 61 FALSE 1 TRUE 2 FALSE FALSE TRUE
214 PT00733 (factor) 83 FALSE 1 TRUE 2 FALSE FALSE TRUE
215 PT00735 (factor) 60 FALSE 1 TRUE 2 FALSE FALSE TRUE
216 PT00736 (factor) 71 TRUE 2 TRUE 2 FALSE FALSE FALSE
217 PT00747 (factor) 67 TRUE 2 TRUE 1 FALSE TRUE FALSE
218 PT00753 (factor) 57 FALSE 1 TRUE 3 FALSE FALSE TRUE
219 PT00756 (factor) 45 TRUE 2 TRUE 1 TRUE TRUE FALSE
220 PT00760 (factor) 72 TRUE 1 TRUE 2 FALSE TRUE FALSE
221 PT00762 (factor) 47 TRUE 1 TRUE 2 FALSE FALSE FALSE
222 PT00764 (factor) 58 TRUE 2 TRUE 2 FALSE FALSE FALSE
223 PT00768 (factor) 80 FALSE 1 TRUE 2 FALSE FALSE FALSE
224 PT00769 (factor) 55 TRUE 1 TRUE 1 FALSE FALSE FALSE
225 PT00773 (factor) 53 TRUE 4 TRUE 2 TRUE TRUE TRUE
226 PT00776 (factor) 90 FALSE 1 TRUE 2 FALSE FALSE FALSE
227 PT00777 (factor) 41 FALSE 1 TRUE 1 FALSE FALSE FALSE
228 PT00778 (factor) 89 FALSE 1 TRUE 2 FALSE FALSE FALSE
229 PT00783 (factor) 56 FALSE 1 TRUE 1 FALSE FALSE FALSE
230 PT00785 (factor) 48 TRUE 1 TRUE 1 FALSE FALSE FALSE
231 PT00788 (factor) 46 FALSE 1 TRUE 3 FALSE TRUE TRUE
232 PT00789 (factor) 48 FALSE 1 TRUE 1 FALSE FALSE FALSE
233 PT00791 (factor) 57 FALSE 1 TRUE 2 TRUE FALSE TRUE
234 PT00793 (factor) 72 FALSE 1 TRUE 1 FALSE FALSE FALSE
235 PT00795 (factor) 53 TRUE 1 TRUE 1 FALSE TRUE FALSE
236 PT00796 (factor) 47 FALSE 2 TRUE 3 FALSE FALSE FALSE
237 PT00801 (factor) 69 FALSE 1 TRUE 1 FALSE FALSE TRUE
238 PT00804 (factor) 65 FALSE 2 TRUE 3 TRUE FALSE FALSE
239 PT00806 (factor) 72 FALSE 1 TRUE 2 FALSE FALSE FALSE
240 PT00807 (factor) 49 TRUE 1 TRUE 3 FALSE TRUE FALSE
241 PT00810 (factor) 46 FALSE 1 TRUE 1 FALSE TRUE FALSE
242 PT00811 (factor) 56 TRUE 1 TRUE 2 FALSE FALSE TRUE
243 PT00827 (factor) 75 TRUE 1 TRUE 1 TRUE FALSE TRUE
244 PT00838 (factor) 56 TRUE 2 TRUE 2 FALSE TRUE TRUE
245 PT00840 (factor) 67 TRUE 2 TRUE 2 FALSE FALSE FALSE
246 PT00841 (factor) 29 FALSE 2 TRUE 3 FALSE FALSE FALSE
247 PT00843 (factor) 81 FALSE 2 TRUE 1 FALSE FALSE FALSE
248 PT00846 (factor) 55 FALSE 1 TRUE 1 TRUE FALSE TRUE
249 PT00847 (factor) 78 FALSE 1 TRUE 1 FALSE FALSE FALSE
250 PT00852 (factor) 65 TRUE 1 TRUE 3 FALSE FALSE FALSE
251 PT00854 (factor) 41 TRUE 1 TRUE 2 FALSE FALSE FALSE
252 PT00855 (factor) 54 TRUE 2 TRUE 1 FALSE TRUE FALSE
253 PT00859 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE TRUE
254 PT00860 (factor) 46 FALSE 1 TRUE 2 FALSE TRUE FALSE
255 PT00866 (factor) 67 TRUE 3 TRUE 2 FALSE TRUE FALSE
256 PT00867 (factor) 58 FALSE 1 TRUE 3 FALSE FALSE FALSE
257 PT00872 (factor) 58 FALSE 3 TRUE 2 FALSE TRUE FALSE
258 PT00873 (factor) 53 FALSE 2 TRUE 3 FALSE FALSE TRUE
259 PT00878 (factor) 69 FALSE 3 TRUE 2 FALSE FALSE FALSE
260 PT00883 (factor) 73 TRUE 1 TRUE 1 FALSE FALSE FALSE
261 PT00892 (factor) 65 TRUE 1 TRUE 2 FALSE FALSE FALSE
262 PT00896 (factor) 75 TRUE 1 TRUE 1 FALSE FALSE FALSE
263 PT00899 (factor) 82 TRUE 2 TRUE 2 NA FALSE TRUE
264 PT00901 (factor) 70 FALSE 2 TRUE 3 FALSE FALSE FALSE
265 PT00903 (factor) 70 TRUE 4 TRUE 1 FALSE FALSE FALSE
266 PT00905 (factor) 35 FALSE 3 TRUE 2 TRUE FALSE FALSE
267 PT00906 (factor) 90 FALSE 1 TRUE 3 FALSE FALSE FALSE
268 PT00907 (factor) 78 TRUE 2 TRUE 1 FALSE TRUE FALSE
269 PT00908 (factor) 32 TRUE 2 TRUE 3 FALSE FALSE FALSE
270 PT00910 (factor) 61 TRUE 2 TRUE 1 TRUE TRUE FALSE
271 PT00912 (factor) 46 TRUE 2 TRUE 2 TRUE TRUE FALSE
272 PT00921 (factor) 72 FALSE 1 TRUE 1 FALSE FALSE FALSE
273 PT00922 (factor) 64 TRUE 4 TRUE 2 TRUE TRUE FALSE
274 PT00932 (factor) 51 FALSE 1 TRUE 2 FALSE FALSE FALSE
275 PT00933 (factor) 69 TRUE 2 TRUE 2 FALSE TRUE FALSE
276 PT00934 (factor) 68 FALSE 1 TRUE 1 FALSE FALSE TRUE
277 PT00935 (factor) 68 FALSE 2 TRUE 2 FALSE FALSE FALSE
278 PT00937 (factor) 50 TRUE 1 TRUE 1 FALSE TRUE TRUE
279 PT00939 (factor) 54 FALSE 1 TRUE 1 FALSE FALSE TRUE
280 PT00944 (factor) 56 FALSE 1 TRUE 2 FALSE FALSE TRUE
281 PT00949 (factor) 48 TRUE 2 TRUE 3 TRUE TRUE TRUE
282 PT00950 (factor) 78 FALSE 1 TRUE 1 FALSE FALSE FALSE
283 PT00952 (factor) 36 TRUE 2 TRUE 2 TRUE TRUE TRUE
284 PT00953 (factor) 37 TRUE 2 TRUE 2 FALSE TRUE FALSE
285 PT00956 (factor) 42 FALSE 1 TRUE 2 FALSE TRUE FALSE
286 PT00963 (factor) 43 FALSE 1 TRUE 2 FALSE TRUE TRUE
287 PT00964 (factor) 77 FALSE 1 TRUE 2 FALSE FALSE FALSE
288 PT00965 (factor) 73 FALSE 1 TRUE 2 FALSE FALSE FALSE
289 PT00970 (factor) 54 FALSE 1 TRUE 2 FALSE FALSE TRUE
290 PT00974 (factor) 69 FALSE 1 TRUE 3 FALSE FALSE FALSE
291 PT00975 (factor) 67 FALSE 2 TRUE 2 TRUE FALSE FALSE
292 PT00976 (factor) 73 TRUE 2 TRUE 3 FALSE FALSE TRUE
293 PT00983 (factor) 67 TRUE 2 TRUE 3 FALSE TRUE FALSE
294 PT00990 (factor) 69 FALSE 1 TRUE 1 FALSE FALSE FALSE
295 PT00998 (factor) 82 FALSE 1 TRUE 3 FALSE FALSE FALSE
296 PT01000 (factor) 43 FALSE 1 TRUE 1 TRUE TRUE FALSE
297 PT01002 (factor) 68 FALSE 1 TRUE 3 FALSE FALSE FALSE
298 PT01006 (factor) 73 FALSE 1 TRUE NA TRUE FALSE FALSE
299 PT01015 (factor) 40 FALSE 2 TRUE 3 TRUE TRUE FALSE
300 PT01018 (factor) 62 FALSE 3 TRUE 2 FALSE FALSE TRUE
301 PT01023 (factor) 72 TRUE 2 TRUE 3 TRUE TRUE TRUE
302 PT01031 (factor) 63 FALSE 1 TRUE 1 FALSE FALSE TRUE
303 PT01032 (factor) 67 FALSE 1 TRUE 1 FALSE FALSE FALSE
304 PT01037 (factor) 48 TRUE 1 TRUE 1 FALSE FALSE TRUE
305 PT01038 (factor) 56 FALSE 1 TRUE 1 FALSE FALSE FALSE
306 PT01042 (factor) 36 TRUE 2 TRUE 2 TRUE FALSE TRUE
307 PT01045 (factor) 64 FALSE 2 TRUE 2 FALSE FALSE FALSE
308 PT01046 (factor) 70 FALSE 1 TRUE 1 FALSE FALSE FALSE
309 PT01051 (factor) 72 TRUE 1 TRUE 2 FALSE TRUE TRUE
310 PT01052 (factor) 63 FALSE 1 TRUE 2 FALSE FALSE TRUE
311 PT01062 (factor) 42 TRUE 1 TRUE 2 NA TRUE FALSE
312 PT01064 (factor) 32 FALSE 1 TRUE 3 FALSE TRUE FALSE
313 PT01067 (factor) 70 FALSE 3 TRUE 3 FALSE TRUE FALSE
314 PT01072 (factor) 71 TRUE 2 TRUE 3 FALSE FALSE FALSE
315 PT01073 (factor) 86 FALSE 1 TRUE 1 FALSE FALSE FALSE
316 PT01074 (factor) 57 TRUE 1 TRUE 3 TRUE FALSE TRUE
317 PT01077 (factor) 66 FALSE 1 TRUE 1 FALSE FALSE TRUE
318 PT01079 (factor) 51 FALSE 1 TRUE 1 FALSE FALSE TRUE
319 PT01081 (factor) 48 TRUE 1 TRUE 1 FALSE FALSE FALSE
320 PT01082 (factor) 49 TRUE 4 TRUE 3 FALSE TRUE FALSE
321 PT01090 (factor) 85 FALSE 3 TRUE 3 FALSE FALSE TRUE
322 PT01095 (factor) 52 TRUE 2 TRUE 2 FALSE TRUE FALSE
323 PT01099 (factor) 72 FALSE 2 TRUE 2 FALSE FALSE TRUE
324 PT01102 (factor) 48 FALSE 2 TRUE 2 TRUE TRUE FALSE
325 PT01104 (factor) 68 FALSE 1 TRUE 2 FALSE FALSE FALSE
326 PT01108 (factor) 38 FALSE 1 TRUE 2 FALSE TRUE TRUE
327 PT01112 (factor) 41 TRUE 1 TRUE 3 FALSE TRUE FALSE
328 PT01122 (factor) 70 FALSE 1 TRUE 3 FALSE FALSE FALSE
329 PT01123 (factor) 68 FALSE 1 TRUE 3 FALSE FALSE FALSE
330 PT01127 (factor) 58 FALSE 4 TRUE 2 FALSE TRUE FALSE
331 PT01128 (factor) 84 FALSE 1 TRUE 1 FALSE FALSE FALSE
332 PT01129 (factor) 35 TRUE 1 TRUE 3 FALSE FALSE TRUE
333 PT01131 (factor) 54 FALSE 4 TRUE 3 FALSE TRUE FALSE
334 PT01134 (factor) 62 TRUE 4 TRUE 3 NA FALSE FALSE
335 PT01136 (factor) 64 TRUE 1 TRUE 2 FALSE FALSE TRUE
336 PT01138 (factor) 55 TRUE 2 TRUE 2 FALSE FALSE TRUE
337 PT01140 (factor) 76 TRUE 3 TRUE 1 FALSE TRUE FALSE
338 PT01141 (factor) 55 TRUE 2 TRUE 2 NA FALSE TRUE
339 PT01146 (factor) 69 FALSE 1 TRUE 1 FALSE FALSE FALSE
340 PT01148 (factor) 45 FALSE 1 TRUE 2 FALSE FALSE TRUE
341 PT01150 (factor) 79 TRUE 4 TRUE 1 FALSE FALSE TRUE
342 PT01152 (factor) 58 FALSE 1 TRUE 2 FALSE FALSE FALSE
343 PT01153 (factor) 59 FALSE 1 TRUE 1 FALSE FALSE TRUE
344 PT01157 (factor) 45 FALSE 1 TRUE 1 FALSE FALSE TRUE
345 PT01162 (factor) 85 TRUE 1 TRUE 2 FALSE FALSE FALSE
346 PT01164 (factor) 35 TRUE 2 TRUE 3 FALSE FALSE FALSE
347 PT01165 (factor) 47 FALSE 1 TRUE NA FALSE FALSE FALSE
348 PT01168 (factor) 73 FALSE 1 TRUE 1 FALSE FALSE TRUE
349 PT01169 (factor) 51 TRUE 3 TRUE 3 TRUE TRUE FALSE
350 PT01175 (factor) 49 TRUE 1 TRUE 2 FALSE FALSE TRUE
351 PT01176 (factor) 38 FALSE 3 TRUE 2 FALSE TRUE FALSE
352 PT01182 (factor) 62 FALSE 2 TRUE 1 FALSE FALSE TRUE
353 PT01183 (factor) 76 FALSE 1 TRUE 2 FALSE FALSE FALSE
354 PT01187 (factor) 72 FALSE 1 TRUE 1 FALSE FALSE TRUE
355 PT01188 (factor) 61 FALSE 2 TRUE 1 FALSE FALSE FALSE
356 PT01189 (factor) 71 FALSE 1 TRUE 1 FALSE FALSE TRUE
357 PT01190 (factor) 74 FALSE 1 TRUE 3 FALSE FALSE FALSE
358 PT01195 (factor) 83 FALSE 1 TRUE 2 FALSE FALSE FALSE
359 PT01198 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE TRUE
360 PT01200 (factor) 58 TRUE 4 TRUE 3 FALSE TRUE TRUE
361 PT01201 (factor) 42 TRUE 3 TRUE 3 FALSE FALSE FALSE
362 PT01203 (factor) 70 FALSE 1 TRUE 1 FALSE FALSE FALSE
363 PT01204 (factor) 75 FALSE 1 TRUE 2 FALSE FALSE FALSE
364 PT01209 (factor) 46 FALSE 2 TRUE 2 FALSE FALSE TRUE
365 PT01213 (factor) 46 FALSE 1 TRUE 2 TRUE TRUE TRUE
366 PT01214 (factor) 74 FALSE 1 TRUE 2 FALSE FALSE TRUE
367 PT01216 (factor) 55 FALSE 1 TRUE 1 FALSE FALSE TRUE
368 PT01218 (factor) 62 TRUE 2 TRUE 2 FALSE FALSE FALSE
369 PT01220 (factor) 49 FALSE 1 TRUE 1 FALSE FALSE FALSE
370 PT01221 (factor) 74 TRUE 2 TRUE 2 FALSE FALSE TRUE
371 PT01225 (factor) 67 FALSE 1 TRUE 2 FALSE FALSE FALSE
372 PT01229 (factor) 55 FALSE 2 TRUE 1 FALSE FALSE TRUE
373 PT01230 (factor) 39 FALSE 1 TRUE 3 FALSE FALSE FALSE
374 PT01233 (factor) 67 TRUE 4 TRUE 3 NA FALSE FALSE
375 PT01236 (factor) 41 TRUE 1 TRUE 1 FALSE FALSE FALSE
376 PT01237 (factor) 78 FALSE 1 TRUE 1 FALSE FALSE TRUE
377 PT01239 (factor) 61 TRUE 2 TRUE 1 FALSE TRUE FALSE
378 PT01241 (factor) 84 FALSE 2 TRUE 1 NA FALSE FALSE
379 PT01242 (factor) 46 TRUE 2 TRUE 2 FALSE TRUE TRUE
380 PT01243 (factor) 65 TRUE 4 TRUE 1 NA FALSE FALSE
381 PT01246 (factor) 69 FALSE 1 TRUE NA FALSE FALSE TRUE
382 PT01250 (factor) 59 FALSE 3 TRUE 3 TRUE FALSE FALSE
383 PT01252 (factor) 65 TRUE 1 TRUE 2 FALSE FALSE FALSE
384 PT01253 (factor) 39 TRUE 2 TRUE 3 NA TRUE TRUE
385 PT01254 (factor) 53 FALSE 1 TRUE 1 FALSE FALSE FALSE
386 PT01257 (factor) 73 FALSE 1 TRUE 1 NA FALSE FALSE
387 PT01258 (factor) 59 FALSE 1 TRUE 1 FALSE FALSE TRUE
388 PT01262 (factor) 53 TRUE 3 TRUE 2 FALSE FALSE FALSE
389 PT01263 (factor) 61 FALSE 1 TRUE 3 FALSE FALSE FALSE
390 PT01264 (factor) 77 TRUE 3 TRUE 3 FALSE FALSE FALSE
391 PT01265 (factor) 84 FALSE 1 TRUE 1 FALSE FALSE FALSE
392 PT01270 (factor) 59 FALSE 2 TRUE 1 FALSE NA NA
393 PT01272 (factor) 67 FALSE 1 TRUE 1 FALSE NA NA
394 PT01273 (factor) 82 FALSE 1 TRUE 2 FALSE FALSE FALSE
395 PT01277 (factor) 72 FALSE 1 TRUE 1 FALSE FALSE FALSE
396 PT01278 (factor) 74 FALSE 1 TRUE 1 FALSE FALSE TRUE
397 PT01279 (factor) 45 FALSE 2 TRUE 1 FALSE FALSE FALSE
398 PT01280 (factor) 73 FALSE 1 TRUE 1 FALSE FALSE TRUE
399 PT01281 (factor) 77 FALSE 1 TRUE 1 FALSE NA NA
400 PT01282 (factor) 33 FALSE 1 TRUE 3 TRUE TRUE TRUE
401 PT01283 (factor) 72 FALSE 1 TRUE 1 FALSE FALSE FALSE
402 PT01284 (factor) 45 TRUE 1 TRUE 2 FALSE TRUE TRUE
403 PT01286 (factor) 61 TRUE 1 TRUE 3 TRUE TRUE TRUE
404 PT01287 (factor) 67 FALSE 1 TRUE 2 FALSE FALSE FALSE
405 PT01288 (factor) 71 FALSE 1 TRUE 1 FALSE NA NA
406 PT01289 (factor) 44 TRUE 3 TRUE 2 NA FALSE FALSE
407 PT01295 (factor) 75 TRUE 2 TRUE 2 FALSE FALSE FALSE
408 PT01296 (factor) 80 FALSE 1 TRUE 1 FALSE NA NA
409 PT01297 (factor) 60 FALSE 2 TRUE 3 FALSE FALSE FALSE
410 PT01298 (factor) 80 FALSE 1 TRUE 3 FALSE FALSE TRUE
411 PT01301 (factor) 66 FALSE 1 TRUE 3 FALSE FALSE FALSE
412 PT01302 (factor) 58 TRUE 1 TRUE 1 FALSE TRUE FALSE
413 PT01309 (factor) 45 FALSE 1 TRUE 2 FALSE FALSE TRUE
414 PT01311 (factor) 69 FALSE 1 TRUE 3 FALSE FALSE TRUE
415 PT01315 (factor) 50 FALSE 1 TRUE 1 FALSE FALSE TRUE
416 PT01316 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE FALSE
417 PT01317 (factor) 65 FALSE 1 TRUE 2 FALSE FALSE TRUE
418 PT01321 (factor) 61 FALSE 1 TRUE 2 FALSE FALSE TRUE
419 PT01322 (factor) 34 TRUE 2 TRUE 2 TRUE FALSE TRUE
420 PT01327 (factor) 64 FALSE 1 TRUE 1 FALSE FALSE FALSE
421 PT01328 (factor) 65 TRUE 2 TRUE 2 FALSE FALSE TRUE
422 PT01331 (factor) 87 TRUE 2 TRUE 1 FALSE FALSE FALSE
423 PT01334 (factor) 53 FALSE 1 TRUE 1 NA FALSE FALSE
424 PT01336 (factor) 55 FALSE 1 TRUE 1 FALSE FALSE FALSE
425 PT01337 (factor) 65 FALSE 2 TRUE 2 FALSE NA NA
426 PT01338 (factor) 50 FALSE 1 TRUE 3 TRUE NA NA
427 PT01339 (factor) 67 FALSE 1 TRUE 3 FALSE FALSE FALSE
428 PT01344 (factor) 50 FALSE 1 TRUE 2 FALSE FALSE TRUE
429 PT01345 (factor) 60 FALSE 1 TRUE 3 FALSE NA NA
430 PT01346 (factor) 68 TRUE 1 TRUE 1 NA NA NA
431 PT01353 (factor) 65 FALSE 1 TRUE 2 FALSE FALSE TRUE
432 PT01355 (factor) 80 FALSE 1 TRUE 1 FALSE FALSE FALSE
433 PT01357 (factor) 42 TRUE 2 TRUE 2 FALSE FALSE FALSE
434 PT01358 (factor) 44 TRUE 2 TRUE 3 FALSE TRUE TRUE
435 PT01363 (factor) 37 TRUE 2 TRUE 3 FALSE TRUE TRUE
436 PT01364 (factor) 67 FALSE 1 TRUE 2 FALSE FALSE FALSE
437 PT01367 (factor) 61 TRUE 1 TRUE 2 FALSE TRUE FALSE
438 PT01369 (factor) 67 TRUE 1 TRUE 3 TRUE FALSE FALSE
439 PT01371 (factor) 65 FALSE 1 TRUE 1 FALSE FALSE TRUE
440 PT01373 (factor) 70 FALSE 2 TRUE 2 FALSE FALSE TRUE
441 PT01384 (factor) 64 FALSE 1 TRUE 1 FALSE FALSE FALSE
442 PT01387 (factor) 64 FALSE 1 TRUE 1 FALSE FALSE FALSE
443 PT01391 (factor) 72 FALSE 4 TRUE 2 FALSE FALSE TRUE
444 PT01398 (factor) 63 TRUE 2 TRUE 3 FALSE NA NA
445 PT01400 (factor) 70 FALSE 1 TRUE 2 NA FALSE TRUE
446 PT01409 (factor) 75 TRUE 2 TRUE 2 FALSE FALSE TRUE
447 PT01413 (factor) 62 FALSE 1 TRUE 2 FALSE FALSE FALSE
448 PT01414 (factor) 52 FALSE 1 TRUE 3 FALSE TRUE TRUE
449 PT01420 (factor) 56 TRUE 2 TRUE 2 FALSE TRUE FALSE
450 PT01421 (factor) 79 FALSE 1 TRUE 1 NA FALSE TRUE
451 PT01423 (factor) 52 FALSE 2 TRUE 1 FALSE FALSE FALSE
452 PT01425 (factor) 80 TRUE 4 TRUE 3 FALSE TRUE TRUE
453 PT01426 (factor) 80 FALSE 2 TRUE 3 FALSE FALSE FALSE
454 PT01430 (factor) 71 FALSE 1 TRUE 2 FALSE FALSE FALSE
455 PT01431 (factor) 74 FALSE 1 TRUE 2 FALSE FALSE FALSE
456 PT01433 (factor) 56 FALSE 1 TRUE 1 FALSE FALSE TRUE
457 PT01434 (factor) 71 FALSE 1 TRUE 2 NA FALSE TRUE
458 PT01444 (factor) 54 FALSE 1 TRUE 3 FALSE FALSE FALSE
459 PT01445 (factor) 60 TRUE 2 TRUE 2 FALSE FALSE FALSE
460 PT01447 (factor) 62 FALSE 1 TRUE 1 FALSE FALSE TRUE
461 PT01449 (factor) 50 TRUE 1 TRUE 3 FALSE FALSE FALSE
462 PT01455 (factor) 59 FALSE 1 TRUE 1 FALSE FALSE TRUE
463 PT01456 (factor) 55 FALSE 1 TRUE 1 TRUE FALSE TRUE
464 PT01460 (factor) 61 FALSE 1 TRUE 1 TRUE FALSE FALSE
465 PT01462 (factor) 54 TRUE 4 TRUE 1 FALSE TRUE TRUE
466 PT01463 (factor) 88 FALSE 1 TRUE 1 FALSE FALSE FALSE
467 PT01465 (factor) 63 FALSE 2 TRUE 3 FALSE FALSE TRUE
468 PT01466 (factor) 44 FALSE 1 TRUE 1 FALSE FALSE FALSE
469 PT01468 (factor) 44 FALSE 1 TRUE 2 FALSE FALSE TRUE
470 PT01471 (factor) 43 TRUE 2 TRUE 3 FALSE TRUE TRUE
471 PT01473 (factor) 72 TRUE 2 TRUE 1 NA NA NA
472 PT01474 (factor) 71 FALSE 1 TRUE 1 FALSE FALSE FALSE
473 PT01475 (factor) 67 TRUE 1 TRUE 2 FALSE FALSE FALSE
474 PT01476 (factor) 80 FALSE 1 TRUE 2 FALSE FALSE TRUE
475 PT01477 (factor) 59 TRUE 1 TRUE 3 NA FALSE FALSE
476 PT01478 (factor) 64 FALSE 1 TRUE 2 FALSE FALSE FALSE
477 PT01481 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE FALSE
478 PT01483 (factor) 46 FALSE 1 TRUE 2 FALSE FALSE TRUE
479 PT01489 (factor) 51 TRUE 1 TRUE 2 FALSE TRUE TRUE
480 PT01490 (factor) 83 TRUE 2 TRUE 3 FALSE FALSE FALSE
481 PT01491 (factor) 42 FALSE 1 TRUE 2 FALSE FALSE FALSE
482 PT01492 (factor) 49 FALSE 1 TRUE 2 FALSE FALSE FALSE
483 PT01494 (factor) 51 FALSE 1 TRUE 1 FALSE FALSE FALSE
484 PT01496 (factor) 66 TRUE 1 TRUE 1 NA FALSE FALSE
485 PT01498 (factor) 54 TRUE 3 TRUE 2 FALSE TRUE TRUE
486 PT01499 (factor) 83 FALSE 1 TRUE 3 FALSE FALSE TRUE
487 PT01503 (factor) 61 TRUE 2 TRUE 2 FALSE FALSE TRUE
488 PT01505 (factor) 43 TRUE 4 TRUE 1 FALSE TRUE FALSE
489 PT01506 (factor) 49 FALSE 2 TRUE 2 FALSE FALSE FALSE
490 PT01507 (factor) 38 TRUE 2 TRUE 3 FALSE TRUE FALSE
491 PT01513 (factor) 50 TRUE 1 TRUE 3 FALSE TRUE TRUE
492 PT01514 (factor) 50 FALSE 2 TRUE 1 FALSE FALSE FALSE
493 PT01516 (factor) 75 FALSE 2 TRUE 1 TRUE FALSE FALSE
494 PT01517 (factor) 73 FALSE 1 TRUE 1 FALSE FALSE FALSE
495 PT01519 (factor) 49 FALSE 1 TRUE 2 FALSE TRUE FALSE
496 PT01520 (factor) 80 FALSE 1 TRUE 1 TRUE FALSE TRUE
497 PT01521 (factor) 77 TRUE 2 TRUE 2 FALSE TRUE FALSE
498 PT01523 (factor) 82 TRUE 1 TRUE 2 FALSE FALSE FALSE
499 PT01524 (factor) 59 FALSE 2 TRUE 1 FALSE FALSE FALSE
500 PT01525 (factor) 63 FALSE 1 TRUE 2 TRUE NA NA
501 PT01529 (factor) 45 FALSE 1 TRUE 3 TRUE FALSE FALSE
502 PT01530 (factor) 65 FALSE 1 TRUE 2 FALSE FALSE TRUE
503 PT01531 (factor) 85 FALSE 1 TRUE 2 FALSE FALSE FALSE
504 PT01532 (factor) 74 TRUE 4 TRUE 3 TRUE FALSE FALSE
505 PT01545 (factor) 66 FALSE 2 TRUE 2 FALSE TRUE FALSE
506 PT01547 (factor) 74 FALSE 1 TRUE 1 NA FALSE FALSE
507 PT01554 (factor) 50 FALSE 1 TRUE 2 FALSE FALSE FALSE
508 PT01555 (factor) 43 TRUE 1 TRUE 2 FALSE TRUE FALSE
509 PT01559 (factor) 55 FALSE 2 TRUE 2 FALSE TRUE TRUE
510 PT01561 (factor) 45 FALSE 2 TRUE 3 FALSE TRUE TRUE
511 PT01563 (factor) 68 TRUE 1 TRUE 2 FALSE FALSE FALSE
512 PT01569 (factor) 46 FALSE 2 TRUE 2 TRUE FALSE FALSE
513 PT01570 (factor) 61 TRUE 2 TRUE 2 FALSE TRUE FALSE
514 PT01571 (factor) 80 TRUE 1 TRUE 3 FALSE FALSE TRUE
515 PT01572 (factor) 67 FALSE 1 TRUE 1 FALSE FALSE FALSE
516 PT01573 (factor) 42 TRUE 2 TRUE 2 FALSE TRUE FALSE
517 PT01578 (factor) 59 FALSE 1 TRUE 2 FALSE FALSE FALSE
518 PT01582 (factor) 71 FALSE 1 TRUE 3 FALSE FALSE TRUE
519 PT01583 (factor) 76 FALSE 1 TRUE 2 FALSE FALSE FALSE
520 PT01587 (factor) 71 FALSE 2 TRUE 2 FALSE FALSE TRUE
521 PT01590 (factor) 60 FALSE 1 TRUE 2 FALSE FALSE TRUE
522 PT01592 (factor) 39 TRUE 1 TRUE 2 FALSE TRUE FALSE
523 PT01593 (factor) 80 FALSE 2 TRUE 3 FALSE FALSE FALSE
524 PT01595 (factor) 38 FALSE 1 TRUE 3 FALSE FALSE FALSE
525 PT01596 (factor) 50 FALSE 1 TRUE 3 FALSE FALSE TRUE
526 PT01597 (factor) 48 TRUE 1 TRUE 2 FALSE TRUE FALSE
527 PT01598 (factor) 63 FALSE 1 TRUE 2 FALSE FALSE TRUE
528 PT01600 (factor) 76 FALSE 2 TRUE 1 FALSE FALSE FALSE
529 PT01701 (factor) 67 TRUE 2 TRUE 2 FALSE FALSE FALSE
530 PT01702 (factor) 71 FALSE 1 TRUE 1 TRUE FALSE FALSE
531 PT01717 (factor) 67 TRUE 2 TRUE 2 NA FALSE TRUE
532 PT01719 (factor) 32 TRUE 4 TRUE 2 FALSE TRUE FALSE
533 PT01724 (factor) 56 TRUE 2 TRUE 3 FALSE FALSE FALSE
534 PT01726 (factor) 72 FALSE 2 TRUE 2 FALSE FALSE FALSE
535 PT01727 (factor) 44 FALSE 2 TRUE 2 FALSE FALSE FALSE
536 PT01732 (factor) 60 FALSE 1 TRUE 1 FALSE FALSE TRUE
537 PT01733 (factor) 60 TRUE 1 TRUE 3 FALSE TRUE TRUE
538 PT01734 (factor) 54 FALSE 1 TRUE 3 FALSE FALSE FALSE
539 PT01736 (factor) 44 FALSE 2 TRUE 1 FALSE FALSE FALSE
540 PT01738 (factor) 57 FALSE 1 TRUE 1 FALSE FALSE FALSE
541 PT01740 (factor) 43 TRUE 1 TRUE 1 FALSE FALSE TRUE
542 PT01744 (factor) 53 FALSE 2 TRUE 1 FALSE FALSE FALSE
543 PT01749 (factor) 74 FALSE 1 TRUE 3 FALSE FALSE FALSE
544 PT02323 (factor) 61 FALSE 1 TRUE 1 FALSE FALSE FALSE
545 PT02329 (factor) 52 TRUE 3 TRUE 2 FALSE TRUE FALSE
546 PT02339 (factor) 63 TRUE 1 TRUE 2 FALSE FALSE FALSE
547 PT02340 (factor) 63 TRUE 1 TRUE 3 TRUE FALSE FALSE
548 PT02355 (factor) 77 FALSE 1 TRUE 2 FALSE FALSE TRUE
549 PT02365 (factor) 73 FALSE 1 TRUE 1 FALSE FALSE FALSE
550 PT02380 (factor) 87 FALSE 1 TRUE 3 FALSE FALSE FALSE
551 PT02382 (factor) 48 FALSE 1 TRUE 1 FALSE FALSE FALSE
552 PT02384 (factor) 73 FALSE 1 TRUE 2 NA FALSE TRUE
553 PT02385 (factor) 86 FALSE 1 TRUE 1 FALSE FALSE TRUE
554 PT02387 (factor) 35 FALSE 1 TRUE 1 FALSE FALSE TRUE
555 PT02400 (factor) 60 TRUE 2 TRUE 2 FALSE FALSE TRUE
556 PT02401 (factor) 67 FALSE 1 TRUE 1 FALSE FALSE TRUE
557 PT02402 (factor) 73 FALSE 2 TRUE 3 TRUE FALSE TRUE
558 PT02403 (factor) 61 TRUE 4 TRUE 3 FALSE FALSE FALSE
559 PT02404 (factor) 63 FALSE 1 TRUE 2 FALSE FALSE FALSE
560 PT02405 (factor) 61 FALSE 1 TRUE 2 TRUE FALSE FALSE
561 PT02408 (factor) 57 TRUE 1 TRUE 3 FALSE TRUE TRUE
562 PT02416 (factor) 55 TRUE 3 TRUE 3 FALSE FALSE FALSE
563 PT02421 (factor) 68 TRUE 1 TRUE 1 FALSE TRUE FALSE
564 PT02422 (factor) 42 FALSE 1 TRUE 2 TRUE FALSE FALSE
565 PT02431 (factor) 61 FALSE 1 TRUE 1 FALSE FALSE TRUE
566 PT02432 (factor) 58 FALSE 1 TRUE 1 FALSE FALSE TRUE
567 PT02435 (factor) 73 TRUE 1 TRUE 1 FALSE FALSE FALSE
568 PT02438 (factor) 52 TRUE 2 TRUE 1 FALSE FALSE FALSE
569 PT02444 (factor) 52 FALSE 1 TRUE 3 FALSE TRUE FALSE
570 PT02445 (factor) 73 FALSE 2 TRUE 3 FALSE FALSE TRUE
571 PT02446 (factor) 44 FALSE 1 TRUE 3 TRUE TRUE TRUE
572 PT02447 (factor) 50 FALSE 2 TRUE 2 FALSE TRUE FALSE
573 PT02450 (factor) 57 FALSE 1 TRUE 2 TRUE FALSE TRUE
574 PT02453 (factor) 47 FALSE 1 TRUE 2 FALSE FALSE TRUE
575 PT02457 (factor) 51 TRUE 1 TRUE 2 FALSE TRUE TRUE
576 PT02461 (factor) 62 FALSE 1 TRUE 1 FALSE FALSE FALSE
577 PT02464 (factor) 71 TRUE 1 TRUE 3 FALSE FALSE FALSE
578 PT02467 (factor) 49 TRUE 2 TRUE 2 FALSE TRUE TRUE
579 PT02475 (factor) 45 TRUE 2 TRUE 2 FALSE FALSE FALSE
580 PT02478 (factor) 34 FALSE 1 TRUE 2 FALSE TRUE TRUE
581 PT02484 (factor) 71 FALSE 1 TRUE 1 FALSE FALSE TRUE
582 PT02489 (factor) 52 FALSE 1 TRUE 2 FALSE FALSE TRUE
583 PT02490 (factor) 75 FALSE 1 TRUE 1 FALSE FALSE FALSE
584 PT02492 (factor) 45 FALSE 4 TRUE 2 FALSE TRUE FALSE
585 PT02494 (factor) 44 FALSE 2 TRUE 1 FALSE TRUE FALSE
586 PT02673 (factor) 64 FALSE 1 TRUE 2 FALSE NA NA
587 PT02676 (factor) 66 TRUE 1 TRUE 2 FALSE NA NA
588 PT02678 (factor) 60 TRUE 1 TRUE 2 FALSE NA NA
589 PT02683 (factor) 66 FALSE 1 TRUE 2 FALSE NA NA
590 PT02684 (factor) 81 FALSE 1 TRUE 2 FALSE NA NA
591 PT02776 (factor) 67 TRUE 2 TRUE 2 FALSE TRUE FALSE
592 PT02779 (factor) 53 FALSE 1 TRUE 2 FALSE TRUE FALSE
593 PT02781 (factor) 51 TRUE 1 TRUE 2 FALSE TRUE TRUE
594 PT02783 (factor) 44 FALSE 1 TRUE 2 FALSE TRUE TRUE
595 PT02786 (factor) 61 TRUE 2 TRUE 3 FALSE TRUE FALSE
596 PT02788 (factor) 82 FALSE 1 TRUE 1 FALSE FALSE FALSE
597 PT02789 (factor) 83 FALSE 1 TRUE 1 FALSE FALSE FALSE
598 PT02791 (factor) 76 FALSE 2 TRUE 2 FALSE FALSE FALSE
599 PT02792 (factor) 39 FALSE 1 TRUE 1 FALSE FALSE FALSE
600 PT02793 (factor) 48 FALSE 1 TRUE 2 FALSE FALSE TRUE
601 PT02800 (factor) 86 FALSE 1 TRUE 1 FALSE FALSE FALSE
602 PT02801 (factor) 42 TRUE 2 TRUE 1 FALSE TRUE TRUE
603 PT02802 (factor) 51 FALSE 1 TRUE 3 FALSE FALSE TRUE
604 PT02804 (factor) 39 FALSE 1 TRUE 1 FALSE FALSE TRUE
605 PT02805 (factor) 57 FALSE 1 TRUE 3 FALSE FALSE FALSE
606 PT02807 (factor) 45 FALSE 1 TRUE 2 FALSE TRUE FALSE
607 PT02810 (factor) 50 TRUE 3 TRUE 2 FALSE TRUE FALSE
608 PT02812 (factor) 66 FALSE 1 TRUE 2 FALSE FALSE FALSE
609 PT02813 (factor) 46 FALSE 1 TRUE 1 FALSE FALSE FALSE
610 PT02814 (factor) 56 FALSE 1 TRUE 1 FALSE FALSE TRUE
611 PT02816 (factor) 53 TRUE 2 TRUE 1 FALSE FALSE FALSE
612 PT02818 (factor) 35 TRUE 2 TRUE 3 TRUE FALSE FALSE
613 PT02822 (factor) 44 FALSE 2 TRUE 2 FALSE FALSE TRUE
614 PT02823 (factor) 82 TRUE 4 TRUE 1 FALSE FALSE FALSE
615 PT02825 (factor) 48 FALSE 1 TRUE 2 FALSE FALSE FALSE
616 PT02826 (factor) 55 FALSE 2 TRUE 1 FALSE FALSE FALSE
617 PT02828 (factor) 52 FALSE 1 TRUE 1 FALSE FALSE TRUE
618 PT02829 (factor) 82 FALSE 1 TRUE 1 FALSE FALSE FALSE
619 PT02830 (factor) 62 FALSE 1 TRUE 1 FALSE FALSE TRUE
620 PT02849 (factor) 81 FALSE 1 TRUE 1 FALSE FALSE FALSE
621 PT02850 (factor) 66 TRUE 2 TRUE 3 FALSE FALSE TRUE
622 PT02852 (factor) 51 TRUE 2 TRUE 3 FALSE TRUE TRUE
horm PFS race
1 <NA> 100+ White
2 not indicated 22 Black
3 <NA> 99+ White
4 not indicated 99+ White
5 done 112 White
6 not indicated 12 Black
7 not indicated 64+ Asian
8 not indicated 56+ White
9 not indicated 79+ White
10 not indicated 26 Black
11 not indicated 73 White
12 not indicated 97+ White
13 not indicated 19 White
14 done 95+ White
15 <NA> 92+ White
16 not indicated 101+ White
17 not indicated 24 White
18 not indicated 84+ White
19 not indicated 89+ White
20 recommended, but not done 10 White
21 recommended, but not done 60 White
22 done 201+ White
23 done 39+ Unknown
24 done 196+ Asian
25 recommended, but not done 165 White
26 recommended, but not done 45 Black
27 recommended, but not done 125+ White
28 recommended, but not done 16+ White
29 done 208+ White
30 done 70+ White
31 recommended, but not done 28 White
32 done 10 White
33 recommended, but not done 160+ White
34 recommended, but not done 18 White
35 recommended, but not done 195+ Black
36 done 47+ Black
37 done 180+ White
38 recommended, but not done 61+ White
39 done 48 White
40 recommended, but not done 95+ Unknown
41 recommended, but not done 105 White
42 done 23 Black
43 recommended, but not done 155+ White
44 recommended, but not done 37+ White
45 not indicated 180+ Black
46 recommended, but not done 18+ White
47 done 204+ White
48 recommended, but not done 63 White
49 recommended, but not done 15+ Black
50 recommended, but not done 188+ White
51 recommended, but not done 210+ White
52 recommended, but not done 105+ White
53 done 37 White
54 not indicated 147+ White
55 recommended, but not done 205+ Black
56 done 198+ Black
57 done 83+ Black
58 not indicated 152+ White
59 done 165+ White
60 done 193+ White
61 <NA> 189+ White
62 not indicated 196+ White
63 not indicated 71+ White
64 done 48+ White
65 not indicated 138+ White
66 not indicated 10 White
67 not indicated 135+ White
68 recommended, but not done 157+ White
69 not indicated 193+ White
70 not indicated 149+ White
71 not indicated 141+ White
72 not indicated 55 White
73 not indicated 177+ White
74 not indicated 189+ White
75 done 55+ White
76 recommended, but not done 165+ White
77 done 203+ White
78 recommended, but not done 80+ White
79 recommended, but not done 189+ White
80 done 144+ White
81 done 135+ White
82 recommended, but not done 90+ White
83 done 94+ White
84 done 146+ White
85 done 163 White
86 recommended, but not done 49 White
87 <NA> 97+ White
88 not indicated 90+ White
89 done 25+ White
90 done 67+ White
91 recommended, but not done 63 White
92 not indicated 23+ White
93 not indicated 128+ White
94 not indicated 52+ White
95 <NA> 15 White
96 not indicated 79 White
97 done 75+ White
98 done 185+ White
99 done 145+ White
100 done 185+ White
101 <NA> 175 White
102 done 107+ White
103 done 161+ Black
104 done 183+ White
105 not indicated 127+ White
106 not indicated 127+ White
107 not indicated 174+ Asian
108 done 108 White
109 not indicated 44 White
110 recommended, but not done 85+ White
111 recommended, but not done 115+ White
112 not indicated 122+ White
113 not indicated 85+ White
114 done 163+ White
115 recommended, but not done 71 White
116 not indicated 93+ Asian
117 done 115+ Asian
118 not indicated 17 White
119 not indicated 165+ Black
120 recommended, but not done 132+ White
121 done 184+ Black
122 recommended, but not done 41 White
123 done 29 White
124 not indicated 24 White
125 done 108+ White
126 not indicated 55+ White
127 done 154+ White
128 recommended, but not done 170+ White
129 recommended, but not done 78+ White
130 not indicated 101+ White
131 done 178+ White
132 done 145+ White
133 not indicated 182+ White
134 recommended, but not done 81 Unknown
135 not indicated 197+ White
136 not indicated 182+ White
137 recommended, but not done 136+ White
138 not indicated 88+ White
139 not indicated 68+ White
140 not indicated 7 Black
141 <NA> 118+ White
142 done 140+ White
143 not indicated 58+ Asian
144 not indicated 94+ White
145 not indicated 169+ White
146 done 84+ White
147 not indicated 125+ White
148 not indicated 167+ White
149 done 73+ White
150 not indicated 97+ White
151 not indicated 164+ White
152 done 117+ White
153 not indicated 116+ White
154 not indicated 71+ White
155 not indicated 129+ White
156 done 150+ White
157 not indicated 43+ White
158 done 130+ White
159 not indicated 150+ White
160 not indicated 152+ White
161 not indicated 140+ Black
162 done 142 Asian
163 not indicated 152+ White
164 not indicated 136+ White
165 not indicated 154+ White
166 not indicated 25 White
167 not indicated 150+ White
168 done 139+ White
169 done 95+ White
170 not indicated 30+ White
171 done 152+ White
172 <NA> 148+ White
173 <NA> 147+ White
174 <NA> 135+ White
175 done 152+ Black
176 <NA> 136 White
177 not indicated 132+ White
178 not indicated 143+ White
179 done 171+ White
180 not indicated 159+ White
181 not indicated 30 White
182 done 42 White
183 not indicated 36 White
184 not indicated 106+ White
185 done 149+ White
186 done 161+ White
187 done 38+ White
188 not indicated 166+ White
189 not indicated 70+ White
190 not indicated 101+ White
191 done 151+ White
192 not indicated 133+ White
193 not indicated 135+ White
194 not indicated 102+ White
195 done 118+ White
196 <NA> 146+ White
197 not indicated 152+ White
198 done 93+ White
199 not indicated 129+ White
200 not indicated 152+ White
201 done 98+ White
202 not indicated 44+ White
203 not indicated 96+ White
204 done 116+ White
205 not indicated 147+ White
206 not indicated 71+ White
207 not indicated 23+ White
208 not indicated 154+ White
209 done 86+ White
210 not indicated 18 White
211 done 141 White
212 not indicated 158+ White
213 not indicated 149+ White
214 done 65+ Unknown
215 recommended, but not done 92+ White
216 not indicated 117+ Black
217 done 18+ White
218 recommended, but not done 71 Black
219 <NA> 150+ White
220 not indicated 47+ White
221 not indicated 139+ White
222 done 39+ White
223 not indicated 33+ Unknown
224 not indicated 150+ Asian
225 not indicated 72+ White
226 not indicated 103+ Black
227 not indicated 130+ Asian
228 not indicated 27+ White
229 not indicated 121+ White
230 <NA> 148+ Unknown
231 not indicated 141+ White
232 not indicated 128+ White
233 not indicated 88 White
234 not indicated 101+ White
235 not indicated 130+ White
236 not indicated 108+ White
237 done 145+ White
238 <NA> 139+ White
239 not indicated 153+ White
240 not indicated 27+ Black
241 not indicated 139+ White
242 not indicated 135+ Unknown
243 not indicated 36+ White
244 recommended, but not done 19 White
245 recommended, but not done 33+ Black
246 recommended, but not done 22 White
247 recommended, but not done 86+ White
248 recommended, but not done 172 White
249 recommended, but not done 129+ White
250 done 121 White
251 recommended, but not done 31+ Unknown
252 recommended, but not done 37+ White
253 recommended, but not done 12+ White
254 recommended, but not done 228+ White
255 recommended, but not done 13 Unknown
256 recommended, but not done 122+ White
257 recommended, but not done 24 Unknown
258 recommended, but not done 172+ Black
259 not indicated 104 White
260 recommended, but not done 86+ Unknown
261 recommended, but not done 117+ White
262 done 47+ Black
263 done 100+ White
264 recommended, but not done 36 Black
265 done 33+ White
266 recommended, but not done 30 White
267 recommended, but not done 43 White
268 recommended, but not done 23+ White
269 recommended, but not done 83 White
270 recommended, but not done 15 Unknown
271 recommended, but not done 32+ Black
272 recommended, but not done 114+ White
273 recommended, but not done 49 White
274 recommended, but not done 13 White
275 done 129+ White
276 not indicated 144+ White
277 recommended, but not done 80+ White
278 <NA> 179+ White
279 not indicated 183+ White
280 not indicated 171+ White
281 done 21 White
282 not indicated 132+ White
283 done 109+ White
284 done 11 White
285 not indicated 172+ White
286 recommended, but not done 172+ White
287 not indicated 110+ White
288 not indicated 93+ Black
289 done 33 White
290 not indicated 124+ White
291 not indicated 124+ White
292 done 22+ White
293 not indicated 68+ White
294 not indicated 175+ White
295 done 82+ White
296 recommended, but not done 132+ White
297 recommended, but not done 160+ White
298 recommended, but not done 206+ White
299 recommended, but not done 18 White
300 done 11 Black
301 done 10 White
302 recommended, but not done 145+ White
303 not indicated 97+ White
304 not indicated 71+ White
305 not indicated 146+ White
306 <NA> 122+ White
307 not indicated 55+ White
308 not indicated 56+ White
309 done 118+ White
310 done 158+ White
311 done 56 White
312 done 101+ White
313 done 21+ White
314 done 5 White
315 recommended, but not done 98+ White
316 done 189+ White
317 recommended, but not done 175+ White
318 done 122+ White
319 recommended, but not done 136 White
320 recommended, but not done 23+ White
321 recommended, but not done 195+ White
322 recommended, but not done 95+ White
323 done 39 White
324 done 238+ Black
325 recommended, but not done 177+ White
326 recommended, but not done 96+ White
327 recommended, but not done 9 White
328 recommended, but not done 83 White
329 recommended, but not done 82+ Unknown
330 done 45 White
331 recommended, but not done 29+ White
332 recommended, but not done 148+ White
333 recommended, but not done 34 White
334 recommended, but not done 44 White
335 done 137+ White
336 done 12 Black
337 recommended, but not done 151+ White
338 recommended, but not done 34+ White
339 recommended, but not done 206+ White
340 recommended, but not done 36 White
341 recommended, but not done 105+ White
342 recommended, but not done 71+ White
343 recommended, but not done 49+ White
344 recommended, but not done 205+ White
345 recommended, but not done 55+ White
346 recommended, but not done 7 Black
347 recommended, but not done 38+ White
348 recommended, but not done 235+ White
349 recommended, but not done 12+ White
350 recommended, but not done 191+ White
351 recommended, but not done 187+ White
352 recommended, but not done 38+ Black
353 recommended, but not done 47 White
354 recommended, but not done 194+ White
355 done 3+ White
356 recommended, but not done 145+ White
357 recommended, but not done 95+ White
358 recommended, but not done 29+ White
359 recommended, but not done 154+ White
360 recommended, but not done 4 Black
361 recommended, but not done 25+ White
362 recommended, but not done 37 White
363 recommended, but not done 198+ White
364 recommended, but not done 45+ White
365 recommended, but not done 214+ White
366 recommended, but not done 179+ White
367 recommended, but not done 118+ White
368 recommended, but not done 18 White
369 recommended, but not done 165+ White
370 done 131 White
371 done 133+ White
372 recommended, but not done 158+ White
373 recommended, but not done 13 White
374 recommended, but not done 11 White
375 recommended, but not done 157+ White
376 recommended, but not done 120+ White
377 recommended, but not done 135+ Black
378 recommended, but not done 108+ White
379 recommended, but not done 83+ Black
380 done 67+ Black
381 recommended, but not done 110+ White
382 recommended, but not done 75+ White
383 recommended, but not done 145+ White
384 not indicated 35 White
385 done 236+ White
386 done 146+ Unknown
387 recommended, but not done 111+ White
388 recommended, but not done 34 White
389 recommended, but not done 135+ White
390 done 70+ White
391 recommended, but not done 115+ White
392 <NA> 59+ Black
393 <NA> 225+ White
394 recommended, but not done 60+ White
395 recommended, but not done 12+ White
396 not indicated 95+ White
397 recommended, but not done 114+ White
398 recommended, but not done 29 White
399 <NA> 129+ White
400 recommended, but not done 51+ White
401 recommended, but not done 153+ White
402 recommended, but not done 174+ White
403 done 58+ White
404 done 97+ White
405 <NA> 231+ White
406 recommended, but not done 45 White
407 recommended, but not done 15+ White
408 <NA> 130+ White
409 recommended, but not done 73 White
410 done 189+ White
411 recommended, but not done 57+ White
412 recommended, but not done 231+ White
413 recommended, but not done 221+ White
414 done 30+ White
415 recommended, but not done 230+ White
416 recommended, but not done 86+ White
417 done 105+ White
418 recommended, but not done 171+ White
419 recommended, but not done 15 Black
420 recommended, but not done 230+ White
421 done 230+ White
422 recommended, but not done 56+ White
423 done 205+ White
424 recommended, but not done 160+ White
425 <NA> 83 White
426 <NA> 233+ White
427 recommended, but not done 203+ White
428 recommended, but not done 28+ White
429 <NA> 231+ White
430 <NA> 181+ White
431 recommended, but not done 67 White
432 done 72+ White
433 recommended, but not done 13+ White
434 done 22 Native Hawaiian or Other Pacific Islander
435 recommended, but not done 54+ White
436 recommended, but not done 148+ White
437 done 94+ White
438 done 131 White
439 recommended, but not done 233+ White
440 recommended, but not done 137+ White
441 done 224 White
442 recommended, but not done 74+ White
443 done 73+ White
444 <NA> 23+ White
445 recommended, but not done 202+ White
446 done 35 White
447 recommended, but not done 211+ White
448 recommended, but not done 131+ White
449 done 103+ White
450 recommended, but not done 53+ White
451 done 145 White
452 recommended, but not done 32+ Black
453 done 58+ Black
454 done 141+ White
455 recommended, but not done 94+ White
456 done 228+ White
457 done 140+ Asian
458 done 95+ White
459 recommended, but not done 129 White
460 recommended, but not done 210+ White
461 recommended, but not done 147+ White
462 recommended, but not done 205+ White
463 done 211+ White
464 recommended, but not done 70+ White
465 recommended, but not done 73+ White
466 recommended, but not done 122+ White
467 recommended, but not done 194+ White
468 recommended, but not done 227+ White
469 recommended, but not done 226+ White
470 recommended, but not done 145 White
471 <NA> 144+ White
472 recommended, but not done 109+ White
473 recommended, but not done 141+ White
474 done 213+ White
475 recommended, but not done 68+ White
476 recommended, but not done 154+ White
477 recommended, but not done 184+ White
478 recommended, but not done 218+ White
479 done 226+ Black
480 recommended, but not done 121+ Unknown
481 recommended, but not done 139+ White
482 recommended, but not done 140+ White
483 done 147+ White
484 recommended, but not done 215+ White
485 recommended, but not done 27 White
486 recommended, but not done 118+ White
487 done 25+ White
488 recommended, but not done 27 Black
489 recommended, but not done 213+ White
490 recommended, but not done 226+ Black
491 done 116 White
492 recommended, but not done 137+ White
493 recommended, but not done 62+ White
494 done 30 White
495 recommended, but not done 27 American Indian or Alaska Native
496 done 39+ White
497 done 8 White
498 recommended, but not done 67+ White
499 recommended, but not done 163+ White
500 <NA> 187+ White
501 done 115+ White
502 recommended, but not done 160 Black
503 recommended, but not done 109+ White
504 done 102+ Black
505 recommended, but not done 126+ White
506 recommended, but not done 131+ Unknown
507 recommended, but not done 227+ White
508 done 70+ Black
509 recommended, but not done 217+ White
510 recommended, but not done 12 Black
511 recommended, but not done 98+ White
512 recommended, but not done 142+ White
513 done 163+ White
514 done 155+ White
515 recommended, but not done 106+ White
516 recommended, but not done 168+ White
517 not indicated 167+ White
518 not indicated 167+ White
519 not indicated 123+ White
520 done 97+ White
521 done 168+ Black
522 not indicated 129+ White
523 not indicated 20+ White
524 not indicated 35+ Unknown
525 done 168+ White
526 not indicated 172+ White
527 not indicated 133+ White
528 done 98+ White
529 done 142+ White
530 recommended, but not done 2+ White
531 done 212+ White
532 done 32 White
533 recommended, but not done 23+ White
534 done 22+ White
535 recommended, but not done 155+ White
536 recommended, but not done 87+ White
537 done 19 White
538 recommended, but not done 56 White
539 recommended, but not done 155+ White
540 recommended, but not done 149+ White
541 recommended, but not done 15 White
542 recommended, but not done 94+ White
543 recommended, but not done 133+ White
544 recommended, but not done 75+ White
545 recommended, but not done 40+ White
546 recommended, but not done 172+ White
547 recommended, but not done 172+ White
548 recommended, but not done 48 Unknown
549 done 221+ White
550 done 10 White
551 recommended, but not done 134+ White
552 done 135+ White
553 not indicated 26+ White
554 done 63 White
555 done 98 White
556 not indicated 192+ White
557 not indicated 123+ White
558 recommended, but not done 27+ Black
559 not indicated 125+ White
560 not indicated 26 White
561 not indicated 17+ Black
562 not indicated 25+ White
563 not indicated 129+ Unknown
564 not indicated 90+ White
565 done 129+ White
566 recommended, but not done 173+ White
567 not indicated 36+ White
568 not indicated 179+ White
569 done 116+ White
570 not indicated 18+ White
571 not indicated 187+ White
572 done 174+ White
573 not indicated 58+ White
574 not indicated 195+ White
575 done 180+ White
576 not indicated 157+ White
577 done 175+ White
578 not indicated 170+ White
579 recommended, but not done 129+ Black
580 recommended, but not done 127+ White
581 recommended, but not done 87+ White
582 done 165+ White
583 done 92+ Black
584 done 102+ White
585 recommended, but not done 109+ White
586 <NA> 189+ White
587 <NA> 101+ White
588 <NA> 197+ White
589 <NA> 59+ White
590 <NA> 15+ White
591 recommended, but not done 39 White
592 done 163+ Black
593 not indicated 170+ White
594 done 117+ White
595 not indicated 137+ White
596 not indicated 112+ White
597 done 42+ White
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602 done 163+ Black
603 done 142+ White
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606 done 161+ White
607 done 75+ White
608 not indicated 104+ White
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611 not indicated 46+ White
612 not indicated 86+ White
613 not indicated 106+ White
614 done 109+ White
615 not indicated 161+ White
616 not indicated 157+ White
617 not indicated 159+ White
618 done 67+ White
619 not indicated 140+ White
620 not indicated 64+ White
621 done 59+ White
622 not indicated 40+ White
logKi67 logKi67q
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- a numeric-hypercolumn of the aggregated sample quantiles
logKi67qperpatientID. These quantiles are calculated at a pre-specified grid of probabilities \(\{p_k, k=1,\cdots,K \} \in [0,1]\). Note that the aggregation must be performed at the level of biologically independent clusters, e.g.,~patientID, to produce independent quantile predictors. - Metadata, including the outcome of interest, e.g., progression free survival
PFS,Her2,HR, etc.
Readers are encouraged to learn more about the hyper data frame (hyperframe) from package spatstat.geom (Baddeley et al. 2015; Baddeley and Turner 2005).
Linear quantile index (QI) (Equation 1.1) is a predictor in a functional generalized linear model (James 2002) for outcomes from the exponential family of distributions, or a linear functional Cox model (Gellar et al. 2015) for survival outcomes,
\[ \text{QI}_{i}=\int_{0}^{1} \beta(p)Q_i(p)dp \tag{1.1}\]
where \(Q_i(p)\) is the (aggregated) sample quantiles logKi67q for the \(i\)-th subject, and \(\beta(p)\) is the unknown coefficient function to be estimated. Listing 1.2 fits a generalized additive model (gam(), Wood 2017, v1.9.4, GPL (>= 2)) with integrated linear spline-based smoothness estimation (s(), Wood 2003, v1.9.4, GPL (>= 2)). This is a scalar-on-function model (Reiss et al. 2017) that predicts a scalar outcome (e.g., progression free survival time PFS[,1L]) using the aggregated quantiles as a functional predictor.
m0
Family: Cox PH
Link function: identity
Formula:
PFS[, 1L] ~ s(logKi67q.x, by = logKi67q.L * logKi67q.y, bs = "cr")
Estimated degrees of freedom:
2 total = 2
REML score: 714.9095
Nonlinear quantile index (nlQI) (Equation 1.2) is a predictor in the functional generalized additive model (McLean et al. 2014) for outcomes from the exponential family of distributions, or an additive functional Cox model (Cui et al. 2021) for survival outcomes.
\[ \text{nlQI}_{i}= \int_{0}^{1} F\big(p, Q_i(p)\big)dp \tag{1.2}\]
where \(F(\cdot,\cdot)\) is an unknown bivariate twice differentiable function. Listing 1.3 fits a generalized additive model (gam(), Wood 2017, v1.9.4, GPL (>= 2)) with tensor product interaction estimation (ti(), Wood 2006, v1.9.4, GPL (>= 2)).
m1
Family: Cox PH
Link function: identity
Formula:
PFS[, 1L] ~ ti(logKi67q.x, logKi67q.y, by = logKi67q.L, bs = "cr",
mc = c(FALSE, TRUE))
Estimated degrees of freedom:
5.32 total = 5.32
REML score: 708.0423
The function widget_gam() creates an interactive htmlwidget (Vaidyanathan et al. 2023, v1.6.4, MIT + file) visualization of the estimated integrand surfaces for the linear (Equation 1.1) or nonlinear quantile index (Equation 1.2) using package plotly (Sievert 2020, v4.12.0, MIT + file). The integrand surfaces, defined on \(p\in[0,1]\) and \(q\in\text{range}\big\{Q_i(p), i=1,\cdots,n\big\}\), are
\[ \hat{S}(p,q) = \begin{cases} \hat{\beta}(p)\cdot q\\ \hat{F}(p,q) \end{cases} \tag{1.3}\]
Also in this interactive visualization are
- the contour lines on the integrand surfaces (Equation 1.3), as well as their projections along the \(s\)-axis, i.e., onto the \((p,q)\)-plane (a.k.a., the “floor”);
- the estimated linear integrand paths \(\hat{\beta}(p)Q_i(p)\) or the nonlinear integrand paths \(\hat{F}(p, Q_i(p))\) on the integrand surfaces (Equation 1.3);
- the sample quantiles \(Q_i(p)\), i.e., the projections of the estimated linear or nonlinear integrand path along the \(s\)-axis, i.e., onto the \((p,q)\)-plane (a.k.a., the “floor”);
- the projections of the estimated linear or nonlinear integrand path along the \(q\)-axis, i.e., onto the \((p,s)\)-plane (a.k.a., the “backwall”), so that the area under each projected path is equal to the estimated linear (Equation 1.1) or nonlinear quantile index (Equation 1.2).
Figure 1.1 is a collage (via package htmltools, Cheng et al. 2025, v0.5.9, GPL (>= 2)) of the interactive htmlwidget visualizations of the linear and nonlinear integrand surfaces, contours, integrand paths and their projections to the “floor” and “backwall”. Listing 1.4 uses n=21L to reduce the htmlwidget objects size.
Code
proj = list(
# x = list(show = TRUE, opacity = .5), # no meaning
y = list(show = TRUE, opacity = .5),
z = list(show = TRUE, opacity = .5)
)
scene = list(
xaxis = list(title = 'Probability (p)', tickformat = '.0%', color = 'dodgerblue'),
yaxis = list(title = 'Quantile (q)', color = 'deeppink'),
zaxis = list(title = 'Integrand (s)', color = 'darkolivegreen')
)
colorscale = list(c(0, 1), c('white', 'lightgreen'))
m0_surface = m0 |>
widget_gam(n.grid = 21L, colorscale = colorscale)
m0_trace = m0 |>
trace_gam(
formula = ~ logKi67q,
projection = proj,
marker = list(size = 1.5)
)
m1_surface = m1 |>
widget_gam(colorscale = colorscale)
m1_trace = m1 |>
trace_gam(
formula = ~ logKi67q,
projection = proj,
marker = list(size = 1.5)
)
htmltools::tagList(
plotly::subplot(m0_surface, m0_trace) |>
plotly::layout(scene = scene),
plotly::subplot(m1_surface, m1_trace) |>
plotly::layout(scene = scene)
) |>
htmltools::browsable()